The Sandman was really the lynchpin of Vertigo in the early days, though we all knew it had a set expiration date. Neil Gaiman had said as much almost from the beginning. When it ended, Vertigo replaced it with the Dreaming, which had it’s moments but never quite captured the wonderful horror edged fantasy that Gaiman had set just inside the borders of the DCU. It was trying to hard to be the Sandman, whereas the Sandman never tried to be anything. It just was.
They also did a bunch of The Sandman Presents mini-series. most have a similar problem, but Love Street stands apart, likely because of the heavy Hellblazer influence. Many of the Dreaming characters are here, but John Constintine really anchors this piece which starts with him as a lad in the 60’s and then fast forewards into the present.
You can skip most of the Sandman sequals, but definitely check into this one for a fun mystic mystery and perhaps a better look at everyone favorite hellblazer.